Betting on NFL Games in Arizona

NFL season is going to be that much bigger in Arizona moving forward. Legal online sports betting is going to help make it that way, and the NFL is the top option to be found on the menu at sportsbooks.

The Arizona Cardinals will naturally be the biggest attraction here at home, but you can expect each NFL game to be heavily bet. There are also plenty of different betting options to explore all season long.

Our complete guide to betting on NFL games in Arizona has all of the ins and outs covered from the best sportsbooks to bet the NFL to the top NFL bets to make. The see this week’s NFL game odds at Arizona online sportsbooks, check our NFL odds page.

Best Arizona online sportsbooks to bet on NFL

Sports bettors have lots of different legal options to explore in Arizona, but some sportsbooks are just better equipped than others. So where are the best places to play?

Here are the top sportsbooks to consider. When you’re ready to get started, click through on our exclusive links to get the best possible sign-up offer.

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What are the most popular NFL bet types?

The NFL attracts a ton of betting volume. When you visit an online sportsbook, you’ll see all of the upcoming games listed out in the main betting lobby once you click on the NFL odds or football tab. For each game, there will be three featured bets and odds attached.

These listing will look something like this at major betting sites, such as BetMGM Arizona, or the BetRivers Sportsbook app:

Los Angeles Rams+120+2.5 (-110)Over 51.5 (-110)
Arizona Cardinals-140-2.5 (-110)Under 51.5 (-110)

These are the main pregame bets for NFL games, each of which have their own rules of the road. Here’s what you need to know.

  • Moneyline: Just pick which side you think will win. There are odds for both choices – negative for favorites and positive for underdogs. The range between the numbers tells you how close of a matchup that oddsmakers are expecting.
  • Spread: Sportsbooks install a spread on each game that’s akin to an estimated margin of victory. You can choose the favorite minus the points or the underdog plus the spread, but the side you pick has to cover.
  • Totals: You can wager on the total number of points that will be scored in the game. Oddsmakers will set the bar with an estimated number. Bettors then get to pick the Over or Under on that amount.

For the moneyline, you’ll see the odds for the two choices, while spreads and totals have two components: the number set by the book and the odds for placing the bet. The moneyline bet is the most straightforward as you make the call on who you think will win. The spread brings more strategy into the argument as the side you pick has to cover the listed number.

For totals, the focus is on how many points the two sides will combine for. No matter which one you choose to bet on, there may be variances to be found in the odds and numbers, so be sure to shop around. Our live odds feed makes it easy to do so as you can compare the lines at the top sportsbooks in an instant.

What are NFL betting apps?

Betting apps are the wave of the future. They’ve taken sports betting by storm as it continues to expand across the United States. These are mobile and online sportsbooks you can use from the comfort of your own home, or anywhere really, as long as you’re within the borders of a state with legalized and regulated gambling. You don’t have to be a resident of that state, just physically located within the state when you place your bets.

However, you can still make your deposits and withdrawals without a geographic restriction. Many of these apps have names you’ve heard plenty of times over the years like FanDuel, DraftKings, and more. All of them have to be licensed within the state before they’re able to offer even a single bet to customers.

To sign up, simply use one of our exclusive links to visit the homepage of the sportsbook. There, you can create an account and register. By using our links and, where required, our promo codes, you’ll get the best bonuses and bonus bets available to new account holders. See our page on Arizona sports betting apps for recommendations.

Once you’re done with those steps, download the app to your preferred mobile device and then deposit. Each sportsbook has its own rules on where a deposit can come from, so make sure to read the terms and conditions, but most of them allow for credit cards and the use of PayPal and other such services.

That’s it. Now you’re ready to place your first NFL wagers, which are as simple as finding the game you want to bet on, clicking to add it to your bet slip, and then confirming you’d like to make that bet.

Keep in mind that these NFL betting apps use geolocation software to keep track of where you are when using the sportsbook. If you aren’t located within the state lines where sports betting is legal and regulated, then the app will not allow you to complete any wagers.

What NFL bets can you make in Arizona?

The main pregame bets drive a lot of the conversation in NFL betting circles, but that’s not all there is to see here. There are plenty of other options to consider, each of which will attract more than their fair share of betting action. Here’s a runthrough of the top choices.


If you click through the individual game listings, you’ll find a wide range of props available. A prop bet can revolve around the game, teams, or individual players. Props can have just two choices or multiple possible selections. Here is an example of a prop you might find at DraftKings Arizona:

  • How many total TDs for Kyler Murray?
    • Over 3.5    +105
    • Under 3.5      -115

Live betting

You can bet in real-time as the action plays out on the field. Live betting is a featured option at all of the top sportsbooks. You’ll see things like updated odds on the main pregame bets and a wide range of props to consider. Here is an example of a live bet at Caesars Sportsbook AZ:

  • Which side will have the halftime lead?
    • San Francisco 49ers        -135
    • Seattle Seahawks        +125


These are long-term wagers that are based on season-long outcomes. Odds for these bet types come out in the offseason with the market staying active from there. Examples of futures bets you could see at FanDuel AZ include:

  • NFC West winner:
    • San Francisco 49ers        +190
    • Los Angeles Rams        +200
    • Seattle Seahawks        +300
    • Arizona Cardinals         +400


For a parlay bet, you’re including two or more selections on the same betting slip. If you’re right on all of your picks, the returns can be great. However, you lose with just one wrong selection.

  • Three-team NFL moneyline parlay:
    • Arizona Cardinals +132 over Tennessee Titans
    • Atlanta Falcons -178 over Philadelphia Eagles
    • Minnesota Vikings -186 over Cincinnati Bengals
    • Total parlay odds: +457

Teasers and pleasers

These are bets for which you can move the spread more to your liking on two or more games. A teaser lessens the risk, while the pleaser adds on additional risk. Odds are based on the amount of the move.

  • Two-team 6-point NFL teaser:
    • Arizona Cardinals -7.5 over Detroit Lions to Cardinals -1.5
    • Kansas City Chiefs -8.5 over Los Angeles Chargers to Chiefs -2.5

Alternate lines

In addition to props, you’ll see alternate lines for each contest when you click through on the main game listing. These are variations on the main listed spreads and totals.

  • Original Over/Under listed at 52.5
    • Range of options above and below that amount with the odds adjusted accordingly.

There are plenty of different ways to bet on the NFL all season long. Options are great to have, but remember that you can always stick to what works best for you. That said, exploring the various bet types as the season plays out to see what works best for you can make it that much more enjoyable.

Any advice for the NFL betting rookie?

Of course. But you may not love it, especially if you’re a big fan of one team or another.

Our key NFL betting tips is to never bet with your heart. Let’s say that together now: Never. Bet. With. Your. Heart.

Always use your head, do your research and make bets based only on solid information and confident reasoning. Sure, you’re going to be wrong more than you’d like, but at least you had quality information on which you staked your hard-earned money.

So don’t just bet on your favorite team to win because you love them. If you can’t stand to bet against them, just don’t do it. Make a plan, use your head, do your research and check your passions at the door.

How to work out your winnings

Reading odds can be a bit difficult for the beginning bettor.

However, once you get the hang of the general concept, it gets a lot easier. And for those who just don’t feel like ever doing any math, there is a cornucopia of betting calculators on the internet.

The simplest way to look at odds is this: when you see a negative number, that is how much money you have to bet in order to win $100; when you see a positive number, that’s how much you’ll win if you wager $100.

Here’s a couple of quick examples:

If you bet on the Arizona Cardinals to beat the San Francisco 49ers and the odds of the former winning a moneyline bet are -130, then you have to wager $130 in order to win that $100. If you do and they indeed come away with the win, then the payout will be $230. That comprises your initial stake of $130 and your profit of $100.

Now, let’s say the Cardinals are playing the Green Bay Packers and are the underdogs at +160. If you have a great source of information that leads you to believe the Packers are going to lose and decide to place $100 on Arizona, then you’d win $260 if you’re right. Again, that’s the $100 from your original bet and the $160 in profit.