The Arizona Cardinals (7-1) visit the San Francisco 49ers (3-4) on Sunday, November 7, 2021 in matchup between NFC West foes at Levi’s Stadium. San Francisco is a 2.5-point underdog. The over/under is set at 46 points for the outing.
Betting Odds
| Favorite | Spread | Favorite Spread Odds | Underdog Spread Odds | Total | Over Total Odds | Under Total Odds |
|---|---|---|---|---|---|---|
| Cardinals | -2.5 | -115 | -105 | 46 | -110 | -110 |
The betting insights in this article reflect betting data from DraftKings as of November 1, 2021, 12:00 AM ET. CLICK HERE to find current betting odds and place a bet at DraftKings Sportsbook.
Cardinals Leaders
- Kyler Murray has passed for 2,276 yards (186-for-256), with 17 touchdowns and seven interceptions (284.5 YPG). He’s also rushed 49 times for 147 yards and three touchdowns.
- Chase Edmonds has churned out a team-leading 427 rushing yards (53.4 per game) plus one touchdown. He has tacked on 30 catches for 211 yards .
- DeAndre Hopkins has reeled in 35 passes for a team-high 486 yards plus seven touchdowns. He averages 60.8 receiving yards per game.
- Murray is the No. 5 fantasy player overall and the No. 5 fantasy quarterback with 177.7 points (averaging 22.2 per game).
- Hopkins’ 90.6 total fantasy points (an average of 11.3 per game), are good enough to rank him 49th overall and 10th among receivers.
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Cardinals Injuries
Cardinals: No Injuries Listed
Head To Head
| Date | Favorite | Home Team | Spread | Total | Favorite Moneyline | Underdog Moneyline | Total Yards | Result |
|---|---|---|---|---|---|---|---|---|
| 12/26/2020 | Cardinals | Cardinals | -5.5 | 49 | -265 | +215 | 398-350 SF | 20-12 SF |
| 9/13/2020 | 49ers | 49ers | -6.5 | 48 | -295 | +255 | 404-366 ARI | 24-20 ARI |
| 11/17/2019 | N/A | 49ers | N/A | N/A | N/A | N/A | 442-266 SF | 36-26 SF |
| 10/31/2019 | N/A | Cardinals | N/A | N/A | N/A | N/A | 411-357 SF | 28-25 SF |
Cardinals Insights
- The Cardinals have averaged 6.4 more points scored this season (30.8) than the 49ers have allowed (24.4).
- When it exceeds what San Francisco gives up this season (24.4 points per game), Arizona is 6-0 and 5-1 against the spread.
- When San Francisco limits opposing offenses to less than 30.8 points, it is 2-4 overall and 3-4 against the spread.
- The 49ers have allowed opposing rushing attacks to average 127.1 yards per game in 2021 compared to the 128.8 yards the Cardinals offense has averaged on the ground per contest.
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Cardinals Schedule
| Date | Opponent | Score | Home/Away | Spread |
|---|---|---|---|---|
| 9/12/2021 | Titans | W 38-13 | Away | +2.5 |
| 9/19/2021 | Vikings | W 34-33 | Home | -3.5 |
| 9/26/2021 | Jaguars | W 31-19 | Away | -8 |
| 10/3/2021 | Rams | W 37-20 | Away | +4 |
| 10/10/2021 | 49ers | W 17-10 | Home | -5.5 |
| 10/17/2021 | Browns | W 37-14 | Away | +3 |
| 10/24/2021 | Texans | W 31-5 | Home | -17.5 |
| 10/28/2021 | Packers | L 24-21 | Home | -6.5 |
| 11/7/2021 | 49ers | – | Away | -2.5 |
| 11/14/2021 | Panthers | – | Home | – |
| 11/21/2021 | Seahawks | – | Away | – |
| 12/5/2021 | Bears | – | Away | – |
| 12/13/2021 | Rams | – | Home | – |
| 12/19/2021 | Lions | – | Away | – |
| 12/25/2021 | Colts | – | Home | – |
| 1/2/2022 | Cowboys | – | Away | – |
| 1/9/2022 | Seahawks | – | Home | – |
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