The Arizona Cardinals (4-0) are favored by 5.5 points as they try to keep their four-game winning streak alive in a matchup with the San Francisco 49ers (2-2) on Sunday, October 10, 2021 at State Farm Stadium. The contest has a point total set at 49.5.
Betting Odds
| Favorite | Spread | Favorite Spread Odds | Underdog Spread Odds | Total | Over Total Odds | Under Total Odds |
|---|---|---|---|---|---|---|
| Cardinals | -5.5 | -115 | -105 | 49.5 | -110 | -110 |
The betting insights in this article reflect betting data from DraftKings as of October 4, 2021, 12:00 AM ET. CLICK HERE to find current betting odds and place a bet at DraftKings Sportsbook.
Cardinals Leaders
- Kyler Murray has thrown for 1,273 yards while connecting on 76.1% of his passes (102-for-134), with nine touchdowns and four interceptions (318.3 yards per game). He’s also run the ball 23 times for 109 yards and three touchdowns.
- Chase Edmonds has churned out a team-best 255 rushing yards (63.8 per game). He has added 20 catches for 140 yards .
- A.J. Green has 15 catches (on 24 targets) and leads the team with 248 receiving yards (62 per game) while hauling in two touchdowns.
- Murray is the No. 2 fantasy player overall and the No. 2 fantasy quarterback with 107.8 points (averaging 27 per game).
- James Conner has recorded 43.8 fantasy points this year (11 per game), enough to rank him 59th overall and 17th among running backs in league-wide fantasy standings.
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Cardinals Injuries
Cardinals: No Injuries Listed
Head To Head
| Date | Favorite | Home Team | Spread | Total | Favorite Moneyline | Underdog Moneyline | Total Yards | Result |
|---|---|---|---|---|---|---|---|---|
| 12/26/2020 | Cardinals | Cardinals | -5.5 | 49 | -265 | +215 | 398-350 SF | 20-12 SF |
| 9/13/2020 | 49ers | 49ers | -6.5 | 48 | -295 | +255 | 404-366 ARI | 24-20 ARI |
| 11/17/2019 | N/A | 49ers | N/A | N/A | N/A | N/A | 442-266 SF | 36-26 SF |
| 10/31/2019 | N/A | Cardinals | N/A | N/A | N/A | N/A | 411-357 SF | 28-25 SF |
Cardinals Insights
- The Cardinals have scored 35 points per game this season, 9.5 more than the 49ers have given up.
- In games where Arizona scores more than 25.5 points, it is 4-0 overall and 3-1 against the spread.
- When the San Francisco defense allows less than 35 points the 49ers have put together a 2-2 overall record and a 1-3 record against the spread.
- The 49ers are conceding 118 yards per game on the ground, compared to the 136.5 rushing yards the Cardinals are accumulating.
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Cardinals Schedule
| Date | Opponent | Score | Home/Away | Spread |
|---|---|---|---|---|
| 9/12/2021 | Titans | W 38-13 | Away | +2.5 |
| 9/19/2021 | Vikings | W 34-33 | Home | -3.5 |
| 9/26/2021 | Jaguars | W 31-19 | Away | -8 |
| 10/3/2021 | Rams | W 37-20 | Away | +4 |
| 10/10/2021 | 49ers | – | Home | -5.5 |
| 10/17/2021 | Browns | – | Away | – |
| 10/24/2021 | Texans | – | Home | – |
| 10/28/2021 | Packers | – | Home | – |
| 11/7/2021 | 49ers | – | Away | – |
| 11/14/2021 | Panthers | – | Home | – |
| 11/21/2021 | Seahawks | – | Away | – |
| 12/5/2021 | Bears | – | Away | – |
| 12/13/2021 | Rams | – | Home | – |
| 12/19/2021 | Lions | – | Away | – |
| 12/25/2021 | Colts | – | Home | – |
| 1/2/2022 | Cowboys | – | Away | – |
| 1/9/2022 | Seahawks | – | Home | – |
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